UniProt SPARQL Endpoint

A standards-compliant SPARQL 1.1 endpoint exposing the full UniProt knowledge graph as RDF. The current release contains approximately 232 billion triples across 21 named graphs. Supports complex biological queries joining protein sequences, annotations, taxonomy, pathways, and cross-references. Powered by QLever. Query timeout is 45 minutes.

API entry from apis.yml

apis.yml Raw ↑
name: UniProt SPARQL Endpoint
description: 'A standards-compliant SPARQL 1.1 endpoint exposing the full UniProt knowledge graph as RDF.
  The current release contains approximately 232 billion triples across 21 named graphs. Supports complex
  biological queries joining protein sequences, annotations, taxonomy, pathways, and cross-references.
  Powered by QLever. Query timeout is 45 minutes.

  '
image: https://www.uniprot.org/images/logos/uniprot.svg
humanURL: https://sparql.uniprot.org/
baseURL: https://sparql.uniprot.org/sparql
version: '2026_01'
tags:
- SPARQL
- RDF
- Semantic Web
- Knowledge Graph
properties:
- type: Documentation
  url: https://sparql.uniprot.org/
- type: TermsOfService
  url: https://www.uniprot.org/help/license
contact:
- FN: UniProt Consortium
  email: [email protected]
  url: https://www.uniprot.org/contact