National Center for Biotechnology Information (NCBI)

PubChem PUG REST API

The PubChem Power User Gateway (PUG) REST API provides programmatic access to PubChem's chemical compound, substance, and bioassay data. Developers can retrieve compound properties, structures, synonyms, and cross-references by name, SMILES, InChI, CID, SID, or AID. The API supports structure search operations and integrates with E-utilities for cross-database queries. Responses are available in JSON, XML, SDF, and other formats.

GitHub

Documentation

📖
documentation
https://pubchem.ncbi.nlm.nih.gov/docs/pug-rest

Other Resources

🔗
rate-limits
https://kinlane.github.io/ncbi/rate-limits/pubchem-pug-rest.yml
🔗
plans
https://kinlane.github.io/ncbi/plans/pubchem-pug-rest.yml

API entry from apis.yml

apis.yml Raw ↑ 
name: PubChem PUG REST API
description: 'The PubChem Power User Gateway (PUG) REST API provides programmatic access to PubChem''s
  chemical compound, substance, and bioassay data. Developers can retrieve compound properties, structures,
  synonyms, and cross-references by name, SMILES, InChI, CID, SID, or AID. The API supports structure
  search operations and integrates with E-utilities for cross-database queries. Responses are available
  in JSON, XML, SDF, and other formats.

  '
image: https://pubchem.ncbi.nlm.nih.gov/favicon.ico
humanURL: https://pubchem.ncbi.nlm.nih.gov/docs/pug-rest
baseURL: https://pubchem.ncbi.nlm.nih.gov/rest/pug
tags:
- Chemistry
- Compounds
- PubChem
- Structures
- Bioassay
properties:
- type: documentation
  url: https://pubchem.ncbi.nlm.nih.gov/docs/pug-rest
- type: rate-limits
  url: https://kinlane.github.io/ncbi/rate-limits/pubchem-pug-rest.yml
- type: plans
  url: https://kinlane.github.io/ncbi/plans/pubchem-pug-rest.yml
contact:
- FN: PubChem Support
  url: https://pubchemdocs.ncbi.nlm.nih.gov/contact