Cradle

Cradle Platform API

The Cradle Platform API is an enterprise REST API for programmatic access to Cradle's AI-driven protein engineering platform. It is organized under per-workspace v2 endpoints and exposes resource groups for Workspaces, Projects, Rounds, Data Management, Tables, Data Loads (file upload/download with finalize, undo, and redo), Artifacts, Tasks, Audit Logs, and Custom Predictors. Task creation endpoints (analyze-data/v2, diversify/v2, engineer/v2, select/v2, search/v2, train/v2) drive Cradle's core generative protein workflows — sequence diversification, multi-property co-optimization, candidate selection, similarity search, and model fine-tuning — and return artifacts that can be inspected, pulled into custom pipelines, or chained into downstream lab automation. The API is paired with an official Python SDK (`cradle-sdk` on PyPI) and a Custom Predictor framework that lets customers register internally developed models against the same orchestration surface used by the Cradle web application. Access is enterprise-gated (no public self-serve tier); authentication and SSO are handled at the workspace level with SOC 2 controls, and the spec is rendered as ReDoc-based reference rather than published as a downloadable OpenAPI file.

Cradle Platform API is published by Cradle on the APIs.io network.

Tagged areas include Protein Engineering, Workspaces, Projects, Rounds, and Data Management. The published artifact set on APIs.io includes API documentation, a getting-started guide, and SDKs.

GitHub

Documentation

📖
Documentation
https://docs.cradle.bio/api/
📖
GettingStarted
https://docs.cradle.bio/docs/getting-started/overview/

SDKs

📦
SDK
https://docs.cradle.bio/sdk/cradle/sdk/

Other Resources

🔗
PythonSDKPackage
https://pypi.org/project/cradle-sdk/
🔗
CustomPredictorTemplate
https://github.com/cradlebio/custom-predictor-template
🔗
SignIn
https://app.cradle.bio

API entry from apis.yml

apis.yml Raw ↑ 
aid: cradle-bio:cradle-platform-api
name: Cradle Platform API
tags:
- Protein Engineering
- Workspaces
- Projects
- Rounds
- Data Management
- Tables
- Data Loads
- Artifacts
- Tasks
- Audit Logs
- Custom Predictors
humanURL: https://docs.cradle.bio/api/
baseURL: https://app.cradle.bio/v2
properties:
- type: Documentation
  url: https://docs.cradle.bio/api/
- type: GettingStarted
  url: https://docs.cradle.bio/docs/getting-started/overview/
- type: SDK
  url: https://docs.cradle.bio/sdk/cradle/sdk/
- type: PythonSDKPackage
  url: https://pypi.org/project/cradle-sdk/
- type: CustomPredictorTemplate
  url: https://github.com/cradlebio/custom-predictor-template
- type: SignIn
  url: https://app.cradle.bio
description: The Cradle Platform API is an enterprise REST API for programmatic access to Cradle's AI-driven
  protein engineering platform. It is organized under per-workspace v2 endpoints and exposes resource
  groups for Workspaces, Projects, Rounds, Data Management, Tables, Data Loads (file upload/download with
  finalize, undo, and redo), Artifacts, Tasks, Audit Logs, and Custom Predictors. Task creation endpoints
  (analyze-data/v2, diversify/v2, engineer/v2, select/v2, search/v2, train/v2) drive Cradle's core generative
  protein workflows — sequence diversification, multi-property co-optimization, candidate selection, similarity
  search, and model fine-tuning — and return artifacts that can be inspected, pulled into custom pipelines,
  or chained into downstream lab automation. The API is paired with an official Python SDK (`cradle-sdk`
  on PyPI) and a Custom Predictor framework that lets customers register internally developed models against
  the same orchestration surface used by the Cradle web application. Access is enterprise-gated (no public
  self-serve tier); authentication and SSO are handled at the workspace level with SOC 2 controls, and
  the spec is rendered as ReDoc-based reference rather than published as a downloadable OpenAPI file.